The term "virtuoso" is applied to a musician considered a master of his or her instrument and the chosen form of musical expression.
Behold Australian Tommy Emmanuel and Hawaiian Jake Shimabukuro playing George Harrison's "While My Guitar Gently Weeps," and know what virtuosity means.
These guys are burning up their uke and guitar and laughing while they do it.
Man. Makes me want to shoot my guitar and put it out of its misery ....